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The impact of acute kidney injury on in-hospital mortality in acute ischemic stroke patients undergoing intravenous thrombolysis.

Florica GadaleanMihaela SimuFlorina Viorica PârvRuxandra VorovenciRaluca TudorAdalbert SchillerRomulus TimarLigia PetricaSilvia VelciovCristina GluhovschiFlaviu BobAdelina MihaescuBogdan TimarGoce SpasovskiViviana Ivan
Published in: PloS one (2017)
The risk of AKI was increased in AIS patients. Thrombolysis itself did not increase the risk of AKI. In the iv. rt-PA patients, as compared to non-AKI, those which developed AKI had a higher rate of in-hospital mortality. The baseline eGFR and the serum uric acid at admission were independent predictors for AKI development in the iv. rt-PA treated AIS patients.
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