Population Pharmacokinetic/Pharmacodynamic Models for P2Y12 Inhibitors: A Systematic Review and Clinical Appraisal Using Exposure Simulation.

Jingcheng ChenYuchen QuMuhan JiangHaiyan LiCheng CuiDongyang Liu

Published in: Clinical pharmacokinetics (2024)

Lowering the maintenance dose of ticagrelor from 90 to 60 mg bid effectively reduces bleeding risk without increasing thrombotic infarction risk in elderly, small-weight Asian females.

Keyphrases

acute coronary syndrome
body mass index
physical activity
weight loss
middle aged
antiplatelet therapy
weight gain
virtual reality