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Population Pharmacokinetic/Pharmacodynamic Models for P2Y12 Inhibitors: A Systematic Review and Clinical Appraisal Using Exposure Simulation.

Jingcheng ChenYuchen QuMuhan JiangHaiyan LiCheng CuiDongyang Liu
Published in: Clinical pharmacokinetics (2024)
Lowering the maintenance dose of ticagrelor from 90 to 60 mg bid effectively reduces bleeding risk without increasing thrombotic infarction risk in elderly, small-weight Asian females.
Keyphrases
  • acute coronary syndrome
  • body mass index
  • physical activity
  • weight loss
  • middle aged
  • antiplatelet therapy
  • weight gain
  • virtual reality