Endothelin-1, Extracellular Volume Overload, and Hemodynamics in Hemodialysis Patients.

Andrew HorvitHaekyung Jeon-SlaughterJaspreet SianBethany RoehmPeter Noel Van Buren

Published in: American journal of hypertension (2024)

In hypertensive HD patients, ET-1 associates with ECV overload higher TPRI and ambulatory BP, and lower CI. Further research is necessary to determine if ECV reduction lowers ET-1 or if pharmacologic ET-1 antagonism can improve outcomes in HD patients with refractory ECV overload.

Keyphrases

blood pressure
end stage renal disease
ejection fraction
newly diagnosed
peritoneal dialysis
type diabetes
metabolic syndrome
skeletal muscle
weight loss
insulin resistance
glycemic control