Cancer-Associated Fibroblasts Together with a Decline in CD8+ T Cells Predict a Worse Prognosis for Breast Cancer Patients.
Hyung Suk KimYung-Kyun NohKyueng Whan MinDong-Hoon KimMi Jung KwonJung Soo PyoJeong-Yeon LeePublished in: Annals of surgical oncology (2023)
This study highlighted the significance of CAFs in breast cancer biology and provided compelling evidence of their impact on patient outcomes and treatment response. The findings offer valuable insights into the potential of CAFs as prognostic and predictive biomarkers and support the development of CAF-targeted therapies to improve breast cancer management.