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UCHL1 Promoted Polarization of M1 Macrophages by Regulating the PI3K/AKT Signaling Pathway.

Yulan HuangShitong HeYitian ChenJunli ShengYuling FuXialin DuYalong YangHonglin LiuZhen-Yu HanYingqi HuangQian WenChaoying ZhouXinying ZhouShengfeng HuLi Ma
Published in: Journal of inflammation research (2022)
In this study, we identified UCHL1 as a positive regulator of M1 macrophage polarization. Our findings may help in developing therapeutic interventions for the treatment of inflammatory diseases and pathogenic infections.
Keyphrases
  • signaling pathway
  • physical activity
  • oxidative stress
  • transcription factor
  • pi k akt
  • combination therapy
  • cell proliferation
  • smoking cessation