UCHL1 Promoted Polarization of M1 Macrophages by Regulating the PI3K/AKT Signaling Pathway.
Yulan HuangShitong HeYitian ChenJunli ShengYuling FuXialin DuYalong YangHonglin LiuZhenyu HanYingqi HuangQian WenChaoying ZhouXinying ZhouShengfeng HuLi MaPublished in: Journal of inflammation research (2022)
In this study, we identified UCHL1 as a positive regulator of M1 macrophage polarization. Our findings may help in developing therapeutic interventions for the treatment of inflammatory diseases and pathogenic infections.