Comparative medical characteristics of ZDF-T2DM rats during the course of development to late stage disease.

Yun-Li PangJing-Wen HuGuang-Long LiuShuai-Yao Lu

Published in: Animal models and experimental medicine (2018)

The results show that the ZDF/T2DM rats have typical clinical, histopathological, and molecular characteristics of human T2DM and thus can be used as an effective model for T2DM drug development and treatment of advanced T2DM.

Keyphrases

glycemic control
endothelial cells
metabolic syndrome
single molecule