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CAND1 orchestrates CRLs through rock and roll.
Yuan Xie
Minglei Zhao
Published in:
Cell (2023)
Proper regulation of protein degradation is essential for cell physiology. In the current issue of Cell, Baek et al. elucidated how a large class of ubiquitin ligase, known as CRL, is assembled and disassembled through a key regulator, CAND1.
Keyphrases
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single cell
cell therapy
transcription factor
mesenchymal stem cells