MiR-146a-5p delivered by hucMSC extracellular vesicles modulates the inflammatory response to sulfur mustard-induced acute lung injury.

Zhipeng PeiJinfeng CenXinkang ZhangChuchu GongMingxue SunWenqi MengGuanchao MaoJingjing WanBingyue HuXiaowen HeQingqiang XuHua HanKai Xiao

Published in: Stem cell research & therapy (2023)

In summary, miR-146a-5p delivered by hucMSC-EVs targeted TRAF6, causing hucMSC-EVs to exert anti-inflammatory effects in SM-induced ALI; thus, hucMSC-EVs treatment may be a promising clinical therapeutic after SM exposure.

Keyphrases

high glucose
diabetic rats
drug induced
cancer therapy
drug delivery