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COVID-19 severity gradient differentially dysregulates clinically relevant drug processing genes in nasopharyngeal swab samples.

Chukwunonso K NwabufoJessica LucAllison McGeerJeremy Alexander HirotaSamira MubarekaAndrew C DoxeyTheo J Moraes
Published in: British journal of clinical pharmacology (2024)
The severity of COVID-19 is associated with the dysregulation of DMETs involved in processing commonly prescribed drugs, suggesting potential disease-drug interactions, especially for narrow therapeutic index drugs.
Keyphrases
  • coronavirus disease
  • sars cov
  • drug induced
  • respiratory syndrome coronavirus
  • risk assessment
  • human health
  • adverse drug