A real-world exploration into clinical outcomes of direct oral anticoagulant therapy in people with chronic kidney disease: a large hospital-based study.

Ezekwesiri Michael NwanosikeHamid A MerchantWendy SunterMuhammad Ayub AnsariBarbara R ConwaySyed Shahzad Hasan

Published in: Journal of nephrology (2024)

A positive effect of DOAC therapy was observed in advanced CKD. Key factors influencing clinical outcomes following DOAC administration in patients in different stages of CKD were identified. These are crucial for designing more advanced studies to explore safer and more effective DOAC therapy for the population.

Keyphrases

chronic kidney disease
end stage renal disease
direct oral anticoagulants
venous thromboembolism
peritoneal dialysis
atrial fibrillation
newly diagnosed
ejection fraction
prognostic factors
stem cells
mesenchymal stem cells
bone marrow
smoking cessation