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Simulations of increased glomerular capillary wall strain in the 5/6-nephrectomized rat.

Owen RichfieldRicardo CortezLuis Gabriel Navar
Published in: Microcirculation (New York, N.Y. : 1994) (2021)
Our findings indicate that glomerular capillary wall strain may deleteriously affect podocytes directly, as well as act in concert with other mechanical changes and environmental factors inherent to the in vivo setting to potentiate glomerular injury in severe renoprival conditions.
Keyphrases
  • high glucose
  • diabetic nephropathy
  • endothelial cells
  • oxidative stress
  • molecular dynamics
  • early onset