TMIGD1 Inhibited Abdominal Adhesion Formation by Alleviating Oxidative Stress in the Mitochondria of Peritoneal Mesothelial Cells.

Yunhua Wu Enmeng Li Zijun Wang Tianli Shen Cong Shen Dong Liu Qiuying Gao Xuqi Li Guangbing Wei

Published in: Oxidative medicine and cellular longevity (2021)

Our findings suggest that TMIGD1 protects mesothelial cells from oxidative stress injury by protecting their mitochondrial function, which is decreased in regular abdominal adhesion tissue. In addition, TMIGD1 enhances peritoneal mesothelial cell adhesion to promote healing.

Keyphrases

cell adhesion
oxidative stress
induced apoptosis
high glucose
endoplasmic reticulum stress
diabetic rats
cell cycle arrest
dna damage
signaling pathway
ischemia reperfusion injury
cell death
biofilm formation
endothelial cells
escherichia coli
reactive oxygen species
cystic fibrosis
endoplasmic reticulum