Assessment High-Risk Breast Cancer in Older Patients: A Comparative Analysis of PREDICT Scores and TAILORx Risk Categorization.
Caglar UnalTolga OzmenÇetin OrduCihan UrasHalil KaraErhan GökmenMustafa ÖzdoğanOrhan DemircanKezban Nur PilancıTomris DuymazVahit ÖzmenPublished in: European journal of breast health (2023)
Our study underscores the importance of using a combination of tools, including the PREDICT tool, PR levels, and TAILORx risk categorization, for a comprehensive risk assessment in these patients, especially in the older population. Accurate risk assessment is crucial for tailoring the treatment and optimizing outcomes in this vulnerable population. Future studies are warranted to further validate these findings in larger cohorts and to explore additional biomarkers and genomic signatures that may aid in the risk assessment and management of breast cancer in older patients.
Keyphrases
- risk assessment
- human health
- heavy metals
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- prognostic factors
- peritoneal dialysis
- gene expression
- genome wide
- breast cancer risk
- copy number
- young adults
- dna methylation
- insulin resistance
- smoking cessation
- combination therapy
- mass spectrometry
- middle aged
- childhood cancer