Rapid, low cost and sensitive detection of Calreticulin mutations by a PCR based amplicon length differentiation assay for diagnosis of myeloproliferative neoplasms.

Ngo Tat TrungDao Thanh QuyenNghiem Xuan HoanDao Phuong GiangTran Thi Huyen TrangThirumalaisamy P VelavanMai Hong BangSong Huu Le

Published in: BMC medical genetics (2019)

PCR-ALDA can be utilized as an easy-to-use, rapid, low cost and sensitive tool in the detection of CALR mutations in Philadelphia-negative MPN patients.

Keyphrases

low cost
loop mediated isothermal amplification
sensitive detection
end stage renal disease
ejection fraction
chronic kidney disease
acute lymphoblastic leukemia
quantum dots
newly diagnosed
peritoneal dialysis