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Primary infection of BALB/c mice with a dengue virus type 4 strain leads to kidney injury.

Arthur da Costa RasinhasFernanda Cunha JácomeGabriela Cardoso CaldasAna Luisa Teixeira de AlmeidaDaniel Dias Coutinho de SouzaJoão Paulo Rodrigues Dos SantosHelver Gonçalves DiasEduarda Lima AraujoRonaldo Mohana-BorgesOrtrud Monika BarthFlavia Barreto Dos SantosDebora Ferreira Barreto-Vieira
Published in: Memorias do Instituto Oswaldo Cruz (2023)
Even though the kidney is probably not a primary target of dengue infection in mice, the inoculation of the virus in the blood appears to damage the renal tissue through local inflammation.
Keyphrases
  • dengue virus
  • zika virus
  • aedes aegypti
  • oxidative stress
  • high fat diet induced
  • type diabetes
  • insulin resistance
  • metabolic syndrome