Human leukocyte antigen mismatch on lung transplantation outcomes.

Ahad FirozMohammed KashemHuaqing ZhaoSteven GeierYoshiya Toyoda

Published in: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery (2022)

This study demonstrates a significant relationship between increased HLA mismatches and BOS development, with decreased overall survival only apparent with 6 mismatches. HLA-A and -DR mismatches were associated with an increased risk of mortality and BOS development compared to groups with at least 1 locus match.

Keyphrases

endothelial cells
extracorporeal membrane oxygenation
magnetic resonance imaging
type diabetes
induced pluripotent stem cells
cardiovascular disease
metabolic syndrome
magnetic resonance
computed tomography
free survival