Targeted Temperature Management for Cardiac Arrest with Nonshockable Rhythm.
Jean-Baptiste LascarrouHamid MerdjiAmélie Le GougeGwenhael ColinGuillaume GrilletPatrick GirardieElisabeth CoupezPierre-François DequinAlain CariouThierry BoulainNoelle BruleJean-Pierre FratPierre AsfarNicolas PichonMickael LandaisGaëtan PlantefeveJean-Pierre QuenotJean-Charles ChakarianMichel SirodotStéphane LegrielJulien LetheulleDidier TheveninArnaud DesachyArnaud DelahayeVlad BotocSylvie VimeuxFrederic MartinoBruno GiraudeauJean Reigniernull nullPublished in: The New England journal of medicine (2019)
Among patients with coma who had been resuscitated from cardiac arrest with nonshockable rhythm, moderate therapeutic hypothermia at 33°C for 24 hours led to a higher percentage of patients who survived with a favorable neurologic outcome at day 90 than was observed with targeted normothermia. (Funded by the French Ministry of Health and others; HYPERION ClinicalTrials.gov number, NCT01994772.).