Effects of the SGLT2 Inhibition on Cardiac Remodeling in Streptozotocin-Induced Diabetic Rats, a Model of Type 1 Diabetes Mellitus.

Camila Moreno RosaDijon Henrique Salome CamposDavid Rafael Abreu ReyesFelipe Cesar DamattoLucas Yamada KurosakiLuana Urbano PaganMariana Janini GomesCamila Renata CorrêaAna Angelica Henrique FernandesMarina Politi OkoshiKatashi Okoshi

Published in: Antioxidants (Basel, Switzerland) (2022)

Dapagliflozin is safe, increases body weight, decreases glycemia and oxidative stress, and attenuates cardiac remodeling in an experimental rat model of Type 1 diabetes mellitus.

Keyphrases

diabetic rats
oxidative stress
body weight
left ventricular
ischemia reperfusion injury
dna damage
induced apoptosis
type diabetes
metabolic syndrome
adipose tissue
diabetic nephropathy
drug induced