Chronic continuous abdominal pain: evaluation of diagnostic features, iatrogenesis and drug treatments in a cohort of 103 patients.
Eleesia KilgallonDipesh Harshvadan VasantDarren GreenPhilip L ShieldsShaheen HamdySimon LalPeter PainePublished in: Alimentary pharmacology & therapeutics (2019)
This is currently the largest cohort CCAP dataset that supports eliciting neuropathic features, including allodynia, for a positive clinical diagnosis, to guide treatment. Physiological exacerbation of CCAP may represent visceral allodynia, and need not preclude central origin. Use of centrally acting neuromodulators, and avoidance of detrimental opioids and surgical interventions appear to predict favourable outcomes.
Keyphrases
- abdominal pain
- end stage renal disease
- neuropathic pain
- ejection fraction
- newly diagnosed
- chronic obstructive pulmonary disease
- chronic kidney disease
- physical activity
- peritoneal dialysis
- prognostic factors
- chronic pain
- emergency department
- patient reported outcomes
- spinal cord injury
- metabolic syndrome
- adipose tissue
- adverse drug
- extracorporeal membrane oxygenation
- weight loss
- smoking cessation