Assessment of serological assays for identifying high titer convalescent plasma.

Christopher W FarnsworthJames B CaseKarl HockRita E ChenJane A O'HalloranRachel PrestiCharles W GossAdriana M RauseoAli EllebedyElitza S TheelMichael S DiamondJeffrey P Henderson

Published in: Transfusion (2021)

Assays based on antibodies against the nucleoprotein were positively associated with neutralizing titers and the Ortho assay, although their ability to distinguish FDA high-titer specimens was imperfect. The resulting relationships help reconcile results from the large body of serological data generated during the COVID-19 pandemic.

Keyphrases

high throughput
electronic health record
machine learning
deep learning
artificial intelligence
ultrasound guided