Tryptophan metabolism and immune alterations in pregnant Hispanic women with chronic Toxoplasma gondii infection.

Stephanie M Prescott Tina MutkaKelley BaumgartelJi Youn YooHailey MorganTeodor T PostolacheAndreas SeyfangJohanna M GostnerDietmar FuchsKami Kim Maureen Wimberly Groer

Published in: American journal of reproductive immunology (New York, N.Y. : 1989) (2023)

Latent T. gondii infection was associated with higher plasma tryptophan levels, and lower inflammatory cytokines across pregnancy, suggesting suppression of the IDO-1 enzyme, and possible T cell exhaustion during pregnancy.

Keyphrases

toxoplasma gondii
pregnant women
preterm birth
pregnancy outcomes
african american