Immune deconvolution and temporal mapping identifies stromal targets and developmental intervals for abrogating murine low-grade optic glioma formation.

Amanda de Andrade CostaJit ChatterjeeOlivia CobbElizabeth CordellAstoria ChaoSuzanne SchaefferAndrea GoldsteinJeffrey R MillmanDavid H Gutmann

Published in: Neuro-oncology advances (2021)

Collectively, these findings provide proof-of-concept demonstrations that targeting stromal support during early gliomagenesis durably blocks murine LGG formation.

Keyphrases

low grade
high grade
bone marrow
high resolution
genome wide
cancer therapy
optical coherence tomography
drug delivery
mass spectrometry
optic nerve