Overexpressing p130/E2F4 in mesenchymal stem cells facilitates the repair of injured alveolar epithelial cells in LPS-induced ARDS mice.

Xiwen ZhangJianxiao ChenMing XueYuying TangJingyuan XuLing LiuYingzi HuangYi YangHaibo QiuFengmei Guo

Published in: Stem cell research & therapy (2019)

Overexpressing p130 or E2F4 in mMSCs could further improve the injured structure and function of epithelial cells in the lungs of ARDS mice as a result of improved differentiation of mMSCs into epithelial cells.

Keyphrases

lps induced
mesenchymal stem cells
acute respiratory distress syndrome
inflammatory response
high fat diet induced
extracorporeal membrane oxygenation
mechanical ventilation
bone marrow
type diabetes
cell therapy
skeletal muscle
adipose tissue