MicroRNA-21 affects mechanical force-induced midpalatal suture remodelling.

Mengying LiZijie ZhangXiuge GuYe JinCheng FengShuangyan YangFulan Wei

Published in: Cell proliferation (2019)

The results showed that miR-21 deficiency reduced the rate of bone formation and prolonged the process of bone formation. miR-21 regulated the bone resorption and osteoclastogenesis by affecting the cell abilities of proliferation and migration.

Keyphrases

cell proliferation
long non coding rna
bone loss
long noncoding rna
single cell
high glucose
bone mineral density
transcription factor
cell therapy
single molecule
soft tissue
inflammatory response
postmenopausal women
lps induced
bone marrow
replacement therapy