Determining breast cancer biomarker status and associated morphological features using deep learning.
Paul GambleRonnachai JaroensriHongwu WangFraser TanMelissa MoranTrissia BrownIsabelle Flament-AuvigneEmad A RakhaMichael TossDavid J DabbsPeter RegitnigNiels OlsonJames H WrenCarrie RobinsonGreg S CorradoLily H PengYuan LiuCraig H MermelDavid F SteinerPo-Hsuan Cameron ChenPublished in: Communications medicine (2021)
This study presents rapid breast cancer biomarker estimation from routine H&E slides and builds on prior advances by prioritizing interpretability of computationally learned features in the context of existing pathological knowledge.