Ceftazidime-avibactam treatment for carbapenemase-producing Enterobacterales in a South African children's hospital.

This study describes ceftazadime-avibactam use in seventeen young children from a resource-constrained-country, where intra-abdominal infection was common. All-cause mortality was 53%. Earlier initiation, dose optimization, recording infusion times and reviewing the need for additional antibiotics were identified as easy-to-implement-antimicrobial-stewardship-interventions.