Validation of the prognostic value of NF-κB p65 in prostate cancer: A retrospective study using a large multi-institutional cohort of the Canadian Prostate Cancer Biomarker Network.

Andrée-Anne Grosset Veronique OuelletChristine CaronGabriela FragosoVéronique BarrèsNathalie DelvoyeMathieu LatourArmen AprikianAlain BergeronSimone ChevalierLadan FazliNeil FleshnerMartin E GleavePierre KarakiewiczLouis LacombeJean-Baptiste LattoufTheodorus van der KwastDominique Trudel Anne-Marie Mes-MassonFred Saadnull null

Published in: PLoS medicine (2019)

We report the first study using the pan-Canadian multi-centre cohorts of CPCBN and validate the association between increased frequency of nuclear p65 frequency and a risk of disease progression.

Keyphrases

prostate cancer
radical prostatectomy
signaling pathway
lps induced
oxidative stress
inflammatory response
toll like receptor