Hepatic stellate cells activate and avoid death under necroptosis stimuli: Hepatic fibrosis during necroptosis.
Ju Hee OhWaqar Khalid SaeedHye Young KimSeung Min LeeA Hyeon LeeGye Ryeol ParkEileen L YoonDae Won JunPublished in: Journal of gastroenterology and hepatology (2023)
HSCs avoid necroptosis due to the absence of MLKL phosphorylation and oligomerization and are activated through autophagosome and NF-κB pathways.