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Clinical presentation, treatment, and genetic and histopathological analysis of juvenile cataracts and secondary glaucoma in a rhesus macaque (Macaca mulatta).

Maria Isabel CasanovaRui ChenLaura M GarzelKatherine J OlstadSoohyun KimRonald Alan HarrisYumei LiMuthuswamy RaveendranQingnan LiangJun WangGlenn YiuJohn Timothy StoutJeffrey A RobertsJeffrey RogersAla MoshiriSara M Thomasy
Published in: Journal of medical primatology (2021)
This report describes the clinical and histological findings, genetic study, and treatment in a 1.3-year-old rhesus macaque with bilateral cataracts and unilateral secondary glaucoma. Intravitreal injection of gentamicin decreased the intraocular pressure from 56 to <2 mm Hg. A putative genetic cause of the cataracts was not identified.
Keyphrases
  • genome wide
  • copy number
  • vascular endothelial growth factor
  • dna methylation
  • case report
  • endothelial cells
  • diabetic retinopathy
  • ultrasound guided
  • smoking cessation