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Contralateral Breast Cancer Risk Among Carriers of Germline Pathogenic Variants in ATM , BRCA1 , BRCA2 , CHEK2 , and PALB2 .

Siddhartha YadavNicholas J BoddickerJie NaEric C PolleyChunling HuSteven N HartRohan D GnanaolivuNicole L LarsonSusan HoltegaardHuaizhi HuangCarolyn A DunnLauren R TerasAlpa V PatelJames V LaceySusan L NeuhausenMaría Elena MartínezChristopher A HaimanFei ChenKathryn J RuddyJanet E OlsonIsabelle DurotAllison W KurianDale R SandlerKatie M O'BrienJack A TaylorClarice R WeinbergHoda Anton-CulverArgyrios ZiogasGary ZirpoliDavid E GoldgarJulie R PalmerSusan M DomchekJeffrey N WeitzelKatherine L NathansonPeter KraftFergus J Couch
Published in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2023)
are at substantially increased risk of CBC and may benefit from enhanced surveillance and risk reduction strategies.
Keyphrases
  • breast cancer risk
  • dna repair
  • dna damage
  • public health
  • copy number
  • dna damage response
  • oxidative stress