G protein-coupled estrogen receptor in the rostral ventromedial medulla contributes to the chronification of postoperative pain.
Jia-Jia XuPo GaoYing WuSu-Qing YinLing ZhuSai-Hong XuDan TangChi-Wai CheungYing-Fu JiaoWei-Feng YuYuan-Hai LiLi-Qun YangPublished in: CNS neuroscience & therapeutics (2021)
Our findings demonstrated that the GPER in the RVM was responsible for the chronification of postoperative pain and the downstream pathway might be involved in MOR phosphorylation.