Pharmacogenomics: a tool to improve medication safety and efficacy in patients with cystic fibrosis.
Colleen M SakonEmma M TillmanPublished in: Pharmacogenomics (2022)
Cystic fibrosis is a genetic, multiorgan system disease that involves the use of many medications to control symptoms associated with the underlying condition. Many of these medications have Clinical Pharmacogenetics Implementation Consortium evidence-based guidelines for pharmacogenomics that are available to guide dosing. The aim of this article is to review relevant literature and evaluate the utility of preemptive pharmacogenomics testing for persons with cystic fibrosis and propose a pharmacogenomics panel that could be considered standard of care for persons with cystic fibrosis.
Keyphrases
- adverse drug
- cystic fibrosis
- healthcare
- clinical decision support
- end stage renal disease
- ejection fraction
- newly diagnosed
- quality improvement
- systematic review
- chronic kidney disease
- primary care
- pseudomonas aeruginosa
- palliative care
- peritoneal dialysis
- gene expression
- prognostic factors
- genome wide
- emergency department
- patient reported outcomes
- chronic pain
- depressive symptoms
- electronic health record
- dna methylation
- sleep quality
- health insurance