The Role of Intraperitoneal Intraoperative Chemotherapy with Paclitaxel in the Surgical Treatment of Peritoneal Carcinomatosis from Ovarian Cancer-Hyperthermia versus Normothermia: A Randomized Controlled Trial.

Angela Casado-AdamLidia Rodriguez-OrtizSebastian Rufian-PeñaCristobal Muñoz-CasaresTeresa Caro-CuencaRosa Ortega-SalasMaria Auxiliadora Fernandez-PeralboMaria Dolores Luque-de-CastroJuan M Sanchez-HidalgoCesar Hervas-MartinezAntonio Romero-RuizJavier BriceñoArjona-Sánchez Álvaro

Published in: Journal of clinical medicine (2022)

The use of intraperitoneal PTX has proven adequate pharmacokinetics with reduction of cell cycle and proliferation markers globally without finding statistically significant differences between its administration under hyperthermia versus normothermia conditions.

Keyphrases

cell cycle
cell proliferation
signaling pathway
patients undergoing
locally advanced
squamous cell carcinoma
radiation therapy