Alterations of the bile microbiome in primary sclerosing cholangitis.
Timur LiwinskiRoman ZenouziClara JohnHanno EhlkenMalte Christoph RühlemannCorinna BangStefan GrothWolfgang LiebMarcus KantowskiNils AndersenGuido SchachschalTom Hemming KarlsenJohannes Roksund HovThomas RöschAnsgar W LohseJoerg HeerenAndre FrankeChristoph SchrammPublished in: Gut (2019)
PSC is characterised by an altered microbiome of the upper alimentary tract and bile ducts. Biliary dysbiosis is linked with increased concentrations of the proinflammatory and potentially cancerogenic agent taurolithocholic acid.
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