Ultrasensitive detection of tumor-specific mutations in saliva of patients with oral cavity squamous cell carcinoma.
Ashwini ShanmugamArun K HariharanRifat HasinaJayalakshmi R NairShanmukh KatragaddaSivaraj IrusappanAarthi RavichandranVamsi VeeramachaneniRadhakrishna BettadapuraMuddasir BhatiVeena RamaswamyVishal U S RaoRitvi K BagadiaAshwini ManjunathN M L ManjunathMonica Charlotte SolomonShiuli MajiUrvashi BahadurChetan BettegowdaNickolas PapadopoulosMark W LingenRamesh HariharanVaijayanti GuptaNishant AgrawalEvgeny IzumchenkoPublished in: Cancer (2020)
The current data highlight the feasibility of somatic mutation identification in driver genes in saliva collected at the time of OCSCC diagnosis.
Keyphrases
- squamous cell carcinoma
- bioinformatics analysis
- label free
- gold nanoparticles
- electronic health record
- genome wide
- big data
- quantum dots
- loop mediated isothermal amplification
- copy number
- real time pcr
- lymph node metastasis
- locally advanced
- genome wide identification
- gene expression
- transcription factor
- data analysis
- genome wide analysis
- deep learning