LOXL1 modulates the malignant progression of colorectal cancer by inhibiting the transcriptional activity of YAP.

Lin HuJing WangYunliang WangLinpeng WuChao WuBo MaoE Maruthi PrasadYuhong WangY Eugene Chin

Published in: Cell communication and signaling : CCS (2020)

LOXL1 may function as an important tumour suppressor in regulating tumour growth, invasion and metastasis via negative regulation of YAP activity. Video abstract.

Keyphrases

signaling pathway
transcription factor
oxidative stress