Diagnostic accuracy of molecular testing with three molecular markers on thyroid fine-needle aspiration cytology with abnormal category.

Hatice ŞeneldirGozde KirTuce SoylemezRabia B GirginNurver OzbayFiliz OzenHandan AnkaraliGurhan BasOrhan Alimoglu

Published in: Diagnostic cytopathology (2020)

The addition of molecular testing with a small panel to FNA cytology may increase the PPV of cytology in abnormal categories. Small panel (BRAF V600E, KRAS, and NRAS) with high specificity and high PPVs may be used particularly for the detection of thyroid malignancy. Cell blocks can be an especially useful and straightforward method for molecular diagnostic studies.

Keyphrases

fine needle aspiration
ultrasound guided
high grade
single molecule
stem cells
wild type
sensitive detection