A woman with progressive motor and cognitive complaints.
Manuel SalavisaDanna KrupkaFilipa SerrazinaPublished in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2023)
We describe the case of a 48-year-old woman presenting with a two-year history of progressive left hemibody-weakness associated with frequent falls, speech difficulties and cognitive dysfunction. Her clinical examination was noticeable for subcortical frontal-predominant cognitive impairment, asymmetrical spastic paraparesis, pseudobulbar findings and delayed horizontal saccade initiation with head-trust phenomenon. Apart from brain atrophy in excess for her age group, the patient's initial cranial-spinal MRI appearances were unremarkable.
Keyphrases
- case report
- multiple sclerosis
- cognitive impairment
- white matter
- resting state
- functional connectivity
- spinal cord
- contrast enhanced
- magnetic resonance imaging
- cerebral palsy
- working memory
- health information
- optic nerve
- botulinum toxin
- upper limb
- computed tomography
- spinal cord injury
- brain injury
- hearing loss
- optical coherence tomography