Leptomeningeal metastatic cells adopt two phenotypic states.
Ján RemšíkYudan ChiXinran TongUgur SenerCamille DerderianAbigail ParkFadi SaadehTejus BaleAdrienne A BoirePublished in: Cancer reports (Hoboken, N.J.) (2020)
Together, these data support mechanistic evidence of a metabolic adaptation that allows cancer cells to thrive in their natural environment but leads to death in vitro.