iTRAQ-based quantitative proteome revealed metabolic changes of Sitophilus zeamais in response to terpinen-4-ol fumigation.

Metabolic changes indicated that terpinen-4-ol could affect the energy supply and potentially be metabolized and detoxified by various enzymes in S. zeamais. The results provide a foundation for further functional studies of key proteins mediated by terpinen-4-ol. © 2018 Society of Chemical Industry.