CENTRAL NERVOUS SYSTEM INFECTION BY GROUP A STREPTOCOCCUS IN CHILDREN IN SPAIN (2019-2023).
Elvira Cobo-VázquezDavid Aguilera-AlonsoVictoria Rello-SaltorAnna GamellIsabel Mellado-SolaManuel Oltra-BenaventLaura Martín-PedrazÁngela Manzanares-CasteleiroJaime Carrasco-ColomEloisa CervantesFrancisco Sanz-SantaeufemiaElena Colino-GilBeatriz Jiménez-MonteroBeatriz SotoCristina CalvoJesús Saavedra-Lozanonull nullPublished in: The Pediatric infectious disease journal (2024)
Central nervous system infections in children caused by group A Streptococcus are rare. This study, conducted across 52 hospitals in Spain from 2019 to 2023, identified 32 cases of central nervous system infections in children caused by group A Streptococcus, with a significant increase from October 2022 onward (1.1% vs. 5.9%, P = 0.002). Half required pediatric intensive care unit admission, 12.5% exhibited sequelae and the mortality rate was 6.2%. Mastoiditis was the predominant primary infection.