Persistence of chloroquine resistance alleles in malaria endemic countries: a systematic review of burden and risk factors.
Moses OcanDickens AkenaSam NsobyaMoses R KamyaRichard SenonoAlison Annet KinengyereEkwaro A ObukuPublished in: Malaria journal (2019)
The prevalence of chloroquine resistance alleles among Plasmodium falciparum parasites have steadily declined since discontinuation of chloroquine use. However, Pfcrt K76T and Pfmdr-1 N86Y mutations still persist at moderate frequencies in most malaria affected countries.