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Persistence of chloroquine resistance alleles in malaria endemic countries: a systematic review of burden and risk factors.

Moses OcanDickens AkenaSam NsobyaMoses R KamyaRichard SenonoAlison Annet KinengyereEkwaro A Obuku
Published in: Malaria journal (2019)
The prevalence of chloroquine resistance alleles among Plasmodium falciparum parasites have steadily declined since discontinuation of chloroquine use. However, Pfcrt K76T and Pfmdr-1 N86Y mutations still persist at moderate frequencies in most malaria affected countries.
Keyphrases
  • plasmodium falciparum
  • risk factors
  • high intensity