5-Aminolevulinic Acid-Guided Resection in Grade III Tumors-A Comparative Cohort Study.

Asfand Baig MirzaJose Pedro LavradorIoannis ChristodoulidesTimothy Martyn BoardmanAmisha VastaniQusai Al BannaRazna AhmedIrena C F NormanChristopher MurphySharmila DeviAnastasios GiamouriadisFrancesco VerganiRichard GullanRanjeev BhangooKeyoumars Ashkan

Published in: Operative neurosurgery (Hagerstown, Md.) (2022)

Despite the benefits of 5-ALA in grade IV glioma surgery, these benefits are limited to a smaller group of patients with grade III tumors where there is sufficient fluorescence to allow GTR. In this cohort of patients, 5-ALA use may result in worse neurological outcomes particularly when GTR is not feasible and therefore caution is warranted.

Keyphrases

end stage renal disease
ejection fraction
minimally invasive
newly diagnosed
chronic kidney disease
photodynamic therapy
prognostic factors
peritoneal dialysis
coronary artery bypass
type diabetes
single molecule
acute coronary syndrome
coronary artery disease
surgical site infection
subarachnoid hemorrhage