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Visible Light-Induced Pericyclic Cascade Reaction for the Synthesis of Quinolinone Derivatives with an Oxabicyclo[4.2.0]octene Skeleton.

Guangxing PanShaoheng QinDawen XuFritz E KühnHao Guo
Published in: Organic letters (2021)
A photoinduced pericyclic cascade reaction has been developed to afford oxabicyclo[4.2.0]octenes. Mechanistic studies show that this reaction undergoes [2 + 2]-photocycloaddition, base-promoted elimination, retro-4π-electrocyclization, [1,5]-H shift, and 4π-electrocyclization procedures. This reaction features wide substrate scope, good functional group tolerance, and excellent diastereoselectivity.
Keyphrases
  • electron transfer
  • visible light
  • high glucose
  • diabetic rats
  • endothelial cells
  • structural basis