The expression and prognostic value of toll-like receptors (TLRs) in pancreatic cancer patients treated with neoadjuvant therapy.

Anna Maria NurmiJaana HagströmHarri MustonenHanna SeppänenCaj Haglund

Published in: PloS one (2022)

We found higher immunopositive intensities among TLRs 1, 3, and 9 in NAT patients. A high TLR1 expression associated with a longer survival among NAT patients, however, among US patients, high expression intensity of TLR5 and TLR7 predicted a favorable postoperative outcome in the adjusted analysis.

Keyphrases

end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
prognostic factors
inflammatory response
toll like receptor
immune response
peritoneal dialysis
stem cells
patient reported outcomes
binding protein
rectal cancer
radiation therapy
patient reported
nuclear factor