Neonatal hyperglycaemia is associated with worse neurodevelopmental outcomes in extremely preterm infants.

Itay ZamirElisabeth Stoltz SjöströmFredrik AhlssonIngrid Hansen-PuppFredrik SereniusMagnus Domellöf

Published in: Archives of disease in childhood. Fetal and neonatal edition (2021)

Neonatal hyperglycaemia >8 mmol/L was associated with lower intelligence scores and worse motor outcomes at 6.5 years of age. Insulin treatment was not associated with either worsened or improved neurodevelopmental outcomes. Randomised controlled trials are needed to clarify the role of insulin in treating hyperglycaemia in extremely preterm infants.

Keyphrases

preterm infants
type diabetes
low birth weight
glycemic control
metabolic syndrome
weight loss