Exploring the Role of the Inhibitor of Apoptosis BIRC6 in Breast Cancer: A Database Analysis.

Santiago M Gómez BergnaAbril MarchesiniLeslie C Amorós MoralesPaula Nazarena ArríasHernán G FarinaVíctor RomanowskiM Florencia GottardoMatias L Pidre

Published in: JCO clinical cancer informatics (2022)

In summary, our in silico data suggest that BIRC6 plays an antiapoptotic, pro-proliferative, and apparent prometastatic role and could be a relevant molecular target for treatment of BC tumors.

Keyphrases

oxidative stress
endoplasmic reticulum stress
cell death
electronic health record
big data
cell cycle arrest
computed tomography
machine learning
diffusion weighted imaging
young adults
cell proliferation
single molecule
artificial intelligence