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In Silico Study to Predict the Structural and Functional Consequences of SNPs on Biomarkers of Ovarian Cancer (OC) and BPA Exposure-Associated OC.

Aeman ZahraMarcia HallJayanta ChatterjeeCristina SisuEmmanouil Karteris
Published in: International journal of molecular sciences (2022)
We demonstrate that the R831C/R804C mutation is deleterious and the predicted ΔΔG values suggest that the mutation reduces the stability of the protein. Future in vitro studies should provide further insight into the role of this transporter protein in UCEC.
Keyphrases
  • protein protein
  • amino acid
  • molecular docking
  • current status
  • gene expression
  • molecular dynamics simulations