Chronic cholestasis detection by a novel tool: automated analysis of cytokeratin 7-stained liver specimens.

Sjöblom NelliSonja BoydAnniina ManninenAnna KnuuttilaSami BlomMartti FärkkiläJohanna Arola

Published in: Diagnostic pathology (2021)

The accuracy of the AI-based analysis was comparable to that of the human K7 score. Automated quantitative image analysis correlated with stage of PSC and with P-ALP. Based on the results of the K7-AI model, we recommend K7 staining in the assessment of cholestasis by means of automated methods that provide fast (9.75 s/specimen) quantitative analysis.

Keyphrases

deep learning
machine learning
artificial intelligence
high throughput
endothelial cells
drug induced
high resolution
induced pluripotent stem cells
label free
flow cytometry