Structure and Dynamics of Large-Scale Cognitive Networks in Huntington's Disease.

Ignacio Aracil-BolañosSaül Martínez-HortaJose M González-de-EchávarriFrederic SampedroJesús Pérez-PérezAndrea HortaAntonia CampolongoCristina IzquierdoBeatriz Gómez-AnsónJavier PagonabarragaJaime Kulisevsky

Published in: Movement disorders : official journal of the Movement Disorder Society (2021)

Huntington's disease shows an early and widespread disruption of large-scale cognitive networks. Importantly, these changes are related to cognitive and disease burden scores, and novel dynamic functional analyses uncovered subtler network changes even in the premanifest stages.

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